Cortisone Injections for Joint Pain: Benefits and Risks Guide

April 1, 2026
OrthoNJ

Cortisone Injections for Joint Pain: A Guide for Patients

This article explains what cortisone shots are, how they work, when they may help, possible risks, how often you can get them, and what to expect before and after the injection. It’s written to help you talk with your OrthoNJ provider and make informed choices about your care.

Cortisone injections are a type of corticosteroid medication delivered directly into a painful joint, tendon area, or around a nerve. They are different from the steroids some people take for muscle building or hormone problems. Cortisone is designed to calm inflammation and can provide meaningful, though usually temporary, pain relief.

At OrthoNJ, we often use cortisone shots as one part of a broader treatment plan that may also include activity changes, physical therapy, oral medicines, and sometimes surgery. Not everyone is a good candidate, and the timing and location of injections matter. Your orthopedic specialist will help you decide if this option fits your situation.

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What is a cortisone injection?

Cortisone is a synthetic form of a hormone your body naturally makes in the adrenal glands. When used as an injection into a joint or the tissues around it, cortisone acts as a strong anti-inflammatory medicine. It doesn’t rebuild cartilage or reverse arthritis, but it often reduces swelling and irritation in the area.

By lowering inflammation, cortisone shots can ease pain, improve motion, and sometimes make physical therapy more comfortable and effective. Relief can last from several days to several months. The timing and degree of benefit are different for each person and for each condition.

Conditions cortisone shots may help

Corticosteroid injections are commonly used throughout the body. Orthopedic specialists often recommend them for painful inflammatory problems in and around joints.

  • Osteoarthritis in joints such as the knee, shoulder, hip, ankle, or base of the thumb
  • Bursitis, including shoulder (subacromial), hip (trochanteric), and knee bursitis
  • Tendinitis and tenosynovitis, such as trigger finger, De Quervain’s tendonitis, and some elbow or shoulder tendon problems
  • Nerve-related pain like carpal tunnel syndrome, when targeted to the area around the nerve
  • Inflammatory arthritis (for example, rheumatoid arthritis) affecting specific joints, often in coordination with your rheumatologist or primary doctor

Not every painful joint benefits from a cortisone shot. Some types of pain are mainly mechanical, structural, or from nerve compression, and may respond better to different treatments. Your OrthoNJ provider will evaluate the source of your symptoms before recommending an injection.

How cortisone shots work

Inflammation is your body’s response to injury or irritation. It can cause swelling, heat, stiffness, and pain. Cortisone interferes with the biochemical pathways that drive inflammation, which can lower those symptoms in the injected area.

When cortisone is injected into a joint or nearby tissues, only a small amount of medicine enters the bloodstream. Most of the effect is local. Some of the steroid is absorbed into the bloodstream and can cause short-term systemic effects, such as temporary increases in blood sugar or other effects in people with diabetes or certain other medical conditions. For that reason clinicians still need a full medical history before giving injections so they can weigh benefits and risks and plan any monitoring you may need.

Who might be a good candidate?

Your orthopedic provider may suggest a cortisone shot if other noninvasive treatments haven’t given enough relief. It can also be used to calm a flare-up so you can better participate in physical therapy or daily activities.

In many cases, we start with options such as rest, activity changes, over-the-counter pain relief, and exercises. A cortisone shot becomes one more option if those steps aren’t enough or if symptoms are severe. In some situations, an injection also helps confirm the source of your pain by showing whether numbing and calming one specific area improves your symptoms.

Who may need extra caution or avoid cortisone?

Cortisone shots aren’t right for everyone. Some medical conditions or medications require extra planning or may make injections unsafe.

  • Diabetes: Cortisone can raise blood sugar for several days, especially with larger doses or multiple injections.
  • Infection risk: Injections shouldn’t be given into or near an active infection, and people with weakened immune systems need careful evaluation.
  • Blood thinners: Medicines that thin your blood may slightly increase bruising or bleeding risk around the injection site.
  • Recent or upcoming surgery: Steroid injections too close to some surgeries can increase infection risk or affect healing.
  • Allergy to injection components: You’ll be asked about any prior reactions to steroids, local anesthetics, or antiseptics.

Always give your OrthoNJ clinician a full list of your health conditions and medications, including over-the-counter drugs and supplements, before scheduling a cortisone shot. This helps the team assess whether any short-term systemic effects are likely and how you should be monitored afterward.

What happens during the procedure?

Cortisone injections are usually done in the office. For some deeper joints, such as the hip or spine, your doctor may use imaging guidance like ultrasound or fluoroscopy to place the needle in the most accurate position.

Most injections take only a few minutes once you’re positioned. You can typically go home shortly afterward and resume normal light activities the same day unless your provider gives you other instructions.

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Step-by-step: what you can expect

  • Preparation: The skin is cleaned thoroughly with antiseptic to lower infection risk.
  • Local numbing: A small amount of local anesthetic may be injected into the skin to reduce discomfort from the main needle.
  • Needle placement: The needle is guided into the joint or target area. You may feel pressure or brief pain.
  • Injection: The cortisone, often mixed with a numbing medicine, is slowly injected.
  • Aftercare: A small bandage is placed, and you receive instructions about activity, ice, and what symptoms to watch for.

How quickly will I feel better?

The numbing medicine, if used, often starts working within minutes and may give short-term relief for several hours. It’s common for pain to return for a day or two after that wears off. The steroid itself usually takes longer to have an effect, often several days and sometimes up to a week or more.

Some people feel clear improvement, some notice only mild change, and a few don’t respond at all. Relief may last from a few weeks to several months when it works well. Because responses are unpredictable, your provider can’t promise a specific level or duration of benefit.

Possible side effects and risks

Cortisone injections have been used for many years and are generally considered safe when used thoughtfully. Still, all medical procedures carry some risk. Your doctor weighs these risks against the potential benefits for your specific case.

Common short-term effects

  • Soreness or aching at the injection site for a day or two
  • A small bruise or mild bleeding under the skin
  • Temporary facial flushing or a warm feeling
  • A brief "steroid flare", where pain worsens for 24 to 48 hours before improving
  • Temporary increase in blood sugar, especially in people with diabetes

Less common but important risks

  • Infection inside the joint or soft tissues, which can be serious and needs prompt care
  • Damage or weakening of nearby tendons with repeated injections
  • Thinning or lightening of the skin or soft tissue at the injection site
  • Very rare reaction to the medicine or preservatives used

Your OrthoNJ clinician will explain the specific risks that apply to the joint or area being treated, how often they occur, and what signs would require urgent follow-up.

How often can I get cortisone injections?

There’s no single rule that fits every patient or every body part. In general, many orthopedic specialists limit cortisone injections in a specific joint to a few times per year. This approach aims to balance symptom relief with the possibility that repeated doses might affect cartilage, tendons, or other tissues.

As a general practice pattern many clinicians try not to exceed about three to four injections per year in the same joint depending on the diagnosis and the patient’s overall health because of concern about potential effects on cartilage or tendons. This is a typical guideline rather than a strict rule, and your provider will individualize the decision based on your health, how well prior injections worked, and other treatment options.

Cortisone shots around the time of surgery

Corticosteroids can affect how the immune system responds and may influence healing. Because of that, many surgeons avoid giving cortisone injections in or near a joint too close to the time of certain operations, especially joint replacements.

Many surgeons avoid injections within a defined window often several weeks to a few months before and after some surgeries. The exact timing should be set by the operating surgeon based on current evidence and your individual situation, so be sure to discuss injection timing with the surgeon if you have upcoming or recent surgery.

How cortisone fits with other treatments

Cortisone shots are usually just one tool in a larger treatment plan. They don’t cure arthritis or other chronic joint problems, but they can help you manage symptoms while you work on other strategies.

  • Physical therapy and exercise: Injections can make it easier to participate fully in therapy, which strengthens the muscles that support your joints.
  • Activity changes: Adjusting how often or how intensely you do certain activities can lower stress on painful joints.
  • Medications: Over-the-counter or prescription pain relievers and anti-inflammatory drugs may still play a role, depending on your health history.
  • Bracing or assistive devices: Splints, braces, or supports may help some conditions, either with or without injections.
  • Surgery: For some people, especially with advanced joint damage or nerve compression, surgery may offer more lasting improvement than repeated injections.

After your cortisone shot: recovery and self-care

Right after the injection, many people can walk or use the arm as usual, but you may be advised to avoid heavy lifting, high-impact exercise, or repetitive strain for a short period. Your provider will give specific guidance based on the area treated.

  • Ice the area as instructed to ease soreness.
  • Watch for increasing redness, warmth, swelling, or fever, which could signal infection.
  • Monitor blood sugars closely if you have diabetes and adjust your management plan with your medical team if needed.
  • Follow your therapy or exercise plan when your doctor says it’s safe to do so, often after the initial soreness improves.

When to call a doctor

Although serious problems after cortisone injections are uncommon, it’s important to know what signs need urgent attention.

  • Severe or rapidly worsening pain, especially if it’s very different from your usual symptoms
  • Increasing redness, warmth, or swelling around the injection site
  • Fever or chills after an injection
  • New numbness, weakness, or difficulty moving the joint
  • Any unusual reaction such as trouble breathing, widespread rash, or facial swelling

If you’re unsure whether what you’re feeling is expected, contact your orthopedic office or another medical professional so they can advise you on the safest next steps.

Talking with your OrthoNJ provider

Before deciding on a cortisone shot, it helps to have a clear conversation about your goals, other treatment options, and the potential benefits and limits of the injection. Bring a list of questions and your full medication and medical history to your visit.

At OrthoNJ, we’ll work with you to weigh cortisone injections against other approaches such as physical therapy, medications, activity changes, or surgery. The right plan is different for each person and often changes over time as your condition and activities change.

Key points to remember

  • Cortisone injections are targeted anti-inflammatory treatments that can reduce pain and swelling in specific joints or soft tissues.
  • They often provide temporary relief and are best used as part of a broader plan that includes exercise, lifestyle changes, and other treatments.
  • Risks are usually low but can include infection, tissue changes, blood sugar spikes, and, with repeated use, possible weakening of tendons or cartilage.
  • How often you can safely receive injections depends on the joint, your diagnosis, your age, and your overall health.
  • Discuss your full medical history and upcoming surgeries with your OrthoNJ provider before having a cortisone shot.

Next steps

If joint or tendon pain is limiting your work, sleep, or activities, consider scheduling an evaluation with OrthoNJ. We’ll review your symptoms, perform a focused exam, and talk through options, which may include cortisone injections, therapy, medications, or other treatments tailored to your needs.

This information is meant for general education and shouldn’t replace a conversation with a qualified medical professional. Your OrthoNJ provider can help you decide whether a cortisone shot is appropriate for your specific condition and health history.

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This treatment info is for informational purposes only. Treatment and recovery vary person to person, and you should consult with your treating physician and team for details on your treatment and recovery process.

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